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Spinal Cord Tumours

The spinal cord stretches from the base of your brain, through the backbone, to your lower back. A spinal cord tumour is an uncontrolled growth of tissue that develops within the spinal cord or surrounding bones, and can be cancerous (malignant), spreading to other parts of the body or noncancerous (benign), remaining as a stationary lump. Spinal cord tumours are classified based on their location in relation to the three protective layers surrounding the spinal cord. Two important types of spinal cord tumours include:

  • Intramedullary tumours: found in the nerve cells within the spinal cord
  • Extramedullary tumours: develop from the cells supporting the spinal cord

Causes of spinal cord tumours are not very clear. They may be inherited, caused due to a genetic defect or may occur due to exposure to certain chemicals. Tumours from various other parts of the body can also spread to the spinal cord.

Symptoms of spinal cord tumours vary based on the type and location of the tumour and may include:

  • Back pain radiating to various parts of your body
  • Reduced sensitivity to pain, heat and cold
  • Reduced or loss of sensation in your arms and legs
  • Weakness of muscles in different parts of your body
  • Loss of bowel movement and bladder function

Spinal tumours are difficult to diagnose due to the similarity of symptoms to other conditions. When you present to the clinic with the above symptoms, your doctor thoroughly reviews your medical history and performs a complete physical and neurological examination. Imaging tests such as MRI and CT scans, and biopsy (examination of a small tissue extracted from the spinal cord) are confirmatory tests that may be ordered to locate the exact position of your tumour.

Treatment for spinal cord tumour is aimed at complete destruction of the tumour and is based on your age, overall health and type of tumour. Some of the treatment options include:

  • Monitoring: Your doctor suggests frequent monitoring of your spinal tumour if it is diagnosed at a very early stage, even before the development of symptoms. This is indicated for the elderly, in whom surgical treatments can pose severe health risks.
  • Surgery: The surgical removal of the tumour is most often the treatment of choice. Tumour excision is performed using high-powered microscopes, while monitoring the functioning of the surrounding nerves and blood vessels in order to reduce the risk of damage to these tissues. Your surgeon may use high-frequency sound waves to first breakdown the tumour into fragments, which can then be easily excised. However, if your tumour cannot be removed completely, surgery will be combined with radiation and/or chemotherapy.
  • Radiation therapy: High energy radiation is used to destroy remnants of spinal tumours after surgery, for those that cannot be treated with surgery or metastatic cancers that have spread from other parts of your body to the spinal cord. Stereotactic radiosurgery (SRS) is a technique where a high dose of radiation is precisely targeted on a tumour to treat it. Radiation treatment may cause side effects such as nausea and vomiting.
  • Chemotherapy: This treatment involves the use of drugs to destroy the tumour cells or restrict their growth. Chemotherapy can also be used in combination with radiation therapy. It may pose side effects such as nausea, fatigue and hair loss.

Other Spine

  • Royal Australasian College of Surgeons: RACS
  • Neurosurgical Society of Australasia
  • Australian Medical Association
  • Cancer Institute NSW
  • Cooperative Trials Group for Neuro-Oncology (COGNO)
  • Australia and New Zealand Melanoma Trials Group (ANZMTG)
  • Society for Neuro-Oncology
  • Sydney Catalyst
  • National Biobanking Consortium for Brain Cancer (NBCBC)
  • Melanoma Institute Australia
  • The University of Sydney
  • University of Notre Dame
  • Royal Prince Alfred Hospital
  • Chris O'Brien Lifehouse
  • Mater Hospital - Sydney